Resources to expand your knowledge

From downloadable handouts to educational videos—we have a variety of resources available to support you.

Not all obesity is the same: explore rare melanocortin-4 receptor (MC4R) pathway diseases

Rare MC4R pathway diseases: mechanism of disease video

Learn more about the MC4R pathway and the role of rare genetic variants in MC4R pathway signaling.

MC4R pathway-associated obesities

Learn about the melanocortin-4 receptor (MC4R) pathway that regulates energy balance, the clinical characteristics of several rare genetic diseases, and when to consider genetic testing.

Bardet-Biedl syndrome (BBS)
Learn about the clinical features, prevalence, pathophysiology, and diagnosis of Bardet-Biedl syndrome, a rare genetic disease. 

BBS: educational video
Learn more about how to diagnose BBS.

Understanding and identifying Bardet-Biedl syndrome (BBS)

Bardet-Biedl syndrome (BBS)
Learn about the clinical features, prevalence, pathophysiology, and diagnosis of Bardet-Biedl syndrome, a rare genetic disease. 

BBS: educational video
Learn more about how to diagnose BBS.

Not all hunger is the same: understanding and identifying hyperphagia 

Hyperphagia questionnaire

Learn how to identify hyperphagia in your patients with rare MC4R pathway diseases, and to determine if/how it is impacting their daily lives.

Rhythm Pharmaceuticals: who we are 

About Rhythm Pharmaceuticals
Learn about Rhythm’s dedication to pioneering research and development of treatments for rare MC4R pathway diseases and our clinical development pipeline.

Genetic testing: uncovering obesity-associated gene variants

Frequency of Obesity-Associated Gene Variants From Uncovering Rare Obesity® Genetic Testing Program
Learn about the frequency of obesity-associated gene variants uncovered in Rhythm’s Uncovering Rare Obesity® testing program

Uncovering Rare Obesity®
Learn about Uncovering Rare Obesity® program, a genetic testing program that helps identify rare genetic diseases of obesity. https://uncoveringrareobesity.com

Ongoing clinical trials

Rhythm’s Clinical Development Program

Acquired Hypothalamic Obesity: Phase 3 Trial Design
Learn about hypothalamic obesity and our ongoing phase 3 clinical trial in patients with acquired hypothalamic obesity.

Discover more

Expand your knowledge of rare genetic variants and their role in MC4R pathway signaling.

BBS, Bardet-Biedl syndrome; LEPR, leptin receptor gene; MC4R, melanocortin-4 receptor; NCOA1, nuclear receptor coactivator 1 gene (also referred to as SRC1); POMC, proopiomelanocortin gene; PCSK1, proprotein convertase subtilisin/kexin type 1 gene